RUBRACA (rucaparib)
TherapyPharma&
RUBRACA (rucaparib) from Pharma& is a PARP inhibitor used in biomarker-defined ovarian and prostate cancers.
Approvals
4
Indications
2
Biomarkers
2
Mapped tests
3
Where this therapy is approved with a companion diagnostic
Each row represents a defined combination of indication, biomarker criteria, and RUBRACA. Select a testing pathway to see the eligible companion diagnostic tests.
Indication-specific approvals
Approvals where RUBRACA is tied to a specific indication and biomarker definition.
| Indication | Biomarker criteria | Notes | |
|---|---|---|---|
Ovarian Cancer Solid Tumor · Ovary | Unknown | View testing pathway → | |
Ovarian Cancer Solid Tumor · Ovary | BRCA1
| View testing pathway → | |
Metastatic Castrate Resistant Prostate Cancer (mCRPC) Solid Tumor · Prostate | BRCA1
| View testing pathway → |
Tumor-agnostic approvals
Approvals defined at the solid tumor level where biomarker criteria determine eligibility for RUBRACA.
No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.
Tests used in these approvals
These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering RUBRACA for eligible patients.
Test
FoundationOne CDx
Foundation Medicine, Inc.
Method
NGS
Specimen
Tissue (FFPE)
1 approvalView test profile →
Test
FoundationOne Liquid CDx
Foundation Medicine, Inc.
Method
NGS
Specimen
Whole blood
2 approvalsView test profile →
Test
BRACAnalysis CDx
Myriad Genetics
Method
PCR
Specimen
Whole blood
1 approvalView test profile →