ENHERTU + PERJETA

Therapy
Approvals
2
Indications
1
Biomarkers
1
Mapped tests
2

Where this therapy is approved with a companion diagnostic

Each row represents a defined combination of indication, biomarker criteria, and ENHERTU + PERJETA. Select a testing pathway to see the eligible companion diagnostic tests.

Indication-specific approvals

Approvals where ENHERTU + PERJETA is tied to a specific indication and biomarker definition.

IndicationBiomarker criteriaNotes
Breast Cancer
Solid Tumor · Breast
ERBB2 (HER2)
  • HER-2 protein overexpression (IHC3+)
View testing pathway →
Tumor-agnostic approvals

Approvals defined at the solid tumor level where biomarker criteria determine eligibility for ENHERTU + PERJETA.

No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.

Tests used in these approvals

These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering ENHERTU + PERJETA for eligible patients.

Test
PATHWAY anti-Her2/neu (4B5) Rabbit Monoclonal Primary Antibody
Ventana Medical Systems, Inc. (Roche Diagnostics)
Method
IHC
Specimen
Tissue (FFPE)
Test
Ventana HER2 Dual ISH DNA Probe Cocktail
Ventana Medical Systems, Inc. (Roche Diagnostics)
Method
ISH
Specimen
Tissue (FFPE)
This view is scoped to ENHERTU + PERJETA. You can also see how it compares with other therapies and indications on the main Know Your Companions™ map.