PCSK1
PCSK1 is involved in hormone processing and metabolic regulation. Pathogenic variants are associated with rare obesity syndromes and guide targeted therapies.
Where this biomarker is used
Each approval combines this biomarker with a specific indication and therapy. Select a therapy in the tables below to open its FDA-defined testing pathway.
Approvals where PCSK1 is defined directly in the indication labeling.
| Indication | Biomarker criteria | Therapies |
|---|---|---|
Obesity Other · Metabolic |
|
Approvals defined at the solid tumor level where PCSK1 is part of the eligibility criteria.
No tumor-agnostic approvals are currently mapped for this biomarker.
Tests that measure this biomarker
These assays report PCSK1 as part of their validated menu. In many cases they are identified in FDA labeling as acceptable companion diagnostics for specific approvals.
Reports PCSK1 as part of its biomarker panel.