VEPANNU (vepdegestrant)

TherapyRigel Pharmaceuticals
Approvals
1
Indications
1
Biomarkers
1
Mapped tests
1

Where this therapy is approved with a companion diagnostic

Each row represents a defined combination of indication, biomarker criteria, and VEPANNU. Select a testing pathway to see the eligible companion diagnostic tests.

Indication-specific approvals

Approvals where VEPANNU is tied to a specific indication and biomarker definition.

IndicationBiomarker criteriaNotes
Breast Cancer
Solid Tumor · Breast
ESR1
  • ESR1 K303R, V422del, L549P, and missense mutations between codons 310 and 547
View testing pathway →
Tumor-agnostic approvals

Approvals defined at the solid tumor level where biomarker criteria determine eligibility for VEPANNU.

No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.

Tests used in these approvals

These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering VEPANNU for eligible patients.

Test
Guardant360 CDx
Guardant Health, Inc.
Method
NGS
Specimen
Plasma
This view is scoped to VEPANNU (vepdegestrant). You can also see how it compares with other therapies and indications on the main Know Your Companions™ map.