TRUQAP (capivasertib)

TherapyAstraZeneca

TRUQAP (capivasertib) from AstraZeneca is an AKT inhibitor used in hormone receptor–positive breast cancer.

Approvals
1
Indications
1
Biomarkers
1
Mapped tests
1

Where this therapy is approved with a companion diagnostic

Each row represents a defined combination of indication, biomarker criteria, and TRUQAP. Select a testing pathway to see the eligible companion diagnostic tests.

Indication-specific approvals

Approvals where TRUQAP is tied to a specific indication and biomarker definition.

IndicationBiomarker criteriaNotes
Metastatic hormone-sensitive prostate cancer (mHSPC)
Solid Tumor
PTEN
  • PTEN protein Loss/Deficient
View testing pathway →
Tumor-agnostic approvals

Approvals defined at the solid tumor level where biomarker criteria determine eligibility for TRUQAP.

No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.

Tests used in these approvals

These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering TRUQAP for eligible patients.

Test
Ventana PTEN (SP218) RxDx Assay
Ventana Medical Systems, Inc. (Roche Diagnostics)
Method
IHC
Specimen
Tissue (FFPE)
This view is scoped to TRUQAP (capivasertib). You can also see how it compares with other therapies and indications on the main Know Your Companions™ map.
TRUQAP (capivasertib) | CDxTests.com | CDx Tests