TALZENNA + XTANDI

Therapy
Approvals
1
Indications
1
Biomarkers
1
Mapped tests
1

Where this therapy is approved with a companion diagnostic

Each row represents a defined combination of indication, biomarker criteria, and TALZENNA + XTANDI. Select a testing pathway to see the eligible companion diagnostic tests.

Indication-specific approvals

Approvals where TALZENNA + XTANDI is tied to a specific indication and biomarker definition.

IndicationBiomarker criteriaNotes
Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Solid Tumor · Prostate
Homologous recombination repair (HRR) genes
  • HRR gene (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, RAD51C) alterations
View testing pathway →
Tumor-agnostic approvals

Approvals defined at the solid tumor level where biomarker criteria determine eligibility for TALZENNA + XTANDI.

No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.

Tests used in these approvals

These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering TALZENNA + XTANDI for eligible patients.

Test
FoundationOne CDx
Foundation Medicine, Inc.
Method
NGS
Specimen
Tissue (FFPE)
This view is scoped to TALZENNA + XTANDI. You can also see how it compares with other therapies and indications on the main Know Your Companions™ map.