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ITOVEBI + IBRANCE + FASLODEX

Therapy

A combination of inavolisib (Genentech), palbociclib (Genentech), and fulvestrant (AstraZeneca) for PIK3CA-altered hormone receptor–positive breast cancer.

Approvals
1
Indications
1
Biomarkers
1
Mapped tests
1

Where this therapy is approved with a companion diagnostic

Each row represents a defined combination of indication, biomarker criteria, and ITOVEBI + IBRANCE + FASLODEX. Select a testing pathway to see the eligible companion diagnostic tests.

Indication-specific approvals

Approvals where ITOVEBI + IBRANCE + FASLODEX is tied to a specific indication and biomarker definition.

IndicationBiomarker criteriaNotes
Breast Cancer
Solid Tumor · Breast
PIK3CA
  • alterations (including mutations)
View testing pathway →
Tumor-agnostic approvals

Approvals defined at the solid tumor level where biomarker criteria determine eligibility for ITOVEBI + IBRANCE + FASLODEX.

No tumor-agnostic companion diagnostic approvals are currently mapped for this therapy.

Tests used in these approvals

These assays are identified in FDA labeling or sponsor materials as companion diagnostics or acceptable tests when considering ITOVEBI + IBRANCE + FASLODEX for eligible patients.

Test
FoundationOne Liquid CDx
Foundation Medicine, Inc.
Method
NGS
Specimen
Whole blood
This view is scoped to ITOVEBI + IBRANCE + FASLODEX. You can also see how it compares with other therapies and indications on the main Know Your Companions™ map.