PD-L1 IHC 28-8 pharmDx
Qualitative IHC assay using rabbit monoclonal anti–PD-L1 (clone 28-8) to assess PD-L1 protein expression in FFPE tumors and support immunotherapy treatment decisions.
Casandra.ai provides a unified ordering experience so you can request this test directly from the performing lab, without changing your workflow.
Ordering is available where Casandra has an active integration with the performing lab. Labs that offer this test can connect with us to enable digital ordering.
About this test
PD-L1 IHC 28-8 pharmDx is an FDA-approved, qualitative immunohistochemical assay that uses monoclonal rabbit anti–PD-L1, clone 28-8, to detect PD-L1 protein in FFPE tumor tissue. Using the EnVision FLEX system on the Autostainer Link 48, it reports the percentage of tumor cells with membrane staining to classify PD-L1 expression and support PD-1/PD-L1–directed treatment decisions.
Where this test fits
| Indication | Biomarker | Biomarker details | Therapy (Select a therapy to open its FDA-approved testing pathway) |
|---|---|---|---|
| Non-Small Cell Lung Cancer (NSCLC) | PD-L1 | protein expression (tumor cell staining ≥1%) | OPDIVO + YERVOY |
IVD Manufacturer
Agilent Technologies Inc. (NYSE: A) is a global leader in analytical and clinical laboratory technologies, delivering insights and innovation that help our customers bring great science to life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.95 billion in fiscal year 2025 and employs approximately 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.
Order this test
If your organization is connected to Casandra, you can place an electronic order forPD-L1 IHC 28-8 pharmDx directly from your existing workflow.
Casandra connects providers, labs, and sponsored programs so that companion diagnostics can be ordered consistently and documented cleanly, regardless of which system you start from.