FOLR1
FOLR1 encodes folate receptor alpha, which is overexpressed in certain ovarian and other cancers. Expression levels may guide eligibility for targeted antibody-drug conjugates.
Where this biomarker is used
Each approval combines this biomarker with a specific indication and therapy. Select a therapy in the tables below to open its FDA-defined testing pathway.
Approvals where FOLR1 is defined directly in the indication labeling.
| Indication | Biomarker criteria | Therapies |
|---|---|---|
Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Solid Tumor · Ovary/Peritoneum |
|
Approvals defined at the solid tumor level where FOLR1 is part of the eligibility criteria.
No tumor-agnostic approvals are currently mapped for this biomarker.
Tests that measure this biomarker
These assays report FOLR1 as part of their validated menu. In many cases they are identified in FDA labeling as acceptable companion diagnostics for specific approvals.
Reports FOLR1 as part of its biomarker panel.