FGFR2

Biomarker

FGFR2 is a receptor tyrosine kinase involved in cell growth and differentiation. Gene fusions and mutations are actionable in specific cancers, including cholangiocarcinoma.

Approvals
1
Indications
1
Therapies
1
Mapped tests
1

Where this biomarker is used

Each approval combines this biomarker with a specific indication and therapy. Select a therapy in the tables below to open its FDA-defined testing pathway.

Indication-specific approvals

Approvals where FGFR2 is defined directly in the indication labeling.

IndicationBiomarker criteriaTherapies
Cholangiocarcinoma
Solid Tumor · Bile Duct
  • fusions and select rearrangements
Tumor-agnostic approvals

Approvals defined at the solid tumor level where FGFR2 is part of the eligibility criteria.

No tumor-agnostic approvals are currently mapped for this biomarker.

Tests that measure this biomarker

These assays report FGFR2 as part of their validated menu. In many cases they are identified in FDA labeling as acceptable companion diagnostics for specific approvals.

Test
FoundationOne CDx
Foundation Medicine, Inc.
Method
NGS
Specimen
Tissue (FFPE)

Reports FGFR2 as part of its biomarker panel.

This view is scoped to FGFR2. You can also see how it compares with other biomarkers and indications on the Know Your Companions™ map.